Getting closer to prediction

Getting closer to p-selectin.

Inflammation is recognized for its important role in the pathophysiology of atherosclerosis (1 ). However, the use of genetic association studies to dissect the impact of inflammatory genes on vascular disease is challenging because of the relatively small effects expected for common variants and the difficulty of identifying surrogates that best reflect underlying disease processes. In this is...

Pharmacogenetics – Getting Closer

This review is written for the generalist to provide an understanding of the application of genetics to the care of patients with glaucoma and the broader concepts of personalized medicine. More specifically, the review will link advances in the genetics of glaucoma with the concepts of pharmacogenetics and its potential to improve patient care.

Vitrification in ART – getting closer?

Background: Twenty five years after the first successful application in mammalian embryology vitrification seems to emerge now from the “new”, “experimental”, “immature” category and has become a method of choice for routine use both in domestic animals and humans. Review: The aim of this review is to summarize major steps of this regretfully slow development, outline the actual possibilities a...

Defining AKI: closer to getting the math right.

quality improvement tool. Psychooncology 2012 46. Holland J, Watson M, Dunn J. The IPOS new International Standard of Quality Cancer Care: integrating the psychosocial domain into routine care. Psychooncology 2012, doi:10.1002/ pon.3116 [Epub ahead of print]. 47. Bultz BD, Groff SL, Fitch M et al. Implementing screening for distress, the 6th vital sign: a Canadian strategy for changing practice...

Why are we not getting any closer to preventing suicide?